Hox Genes: The Instructors Working at Motor Pools

نویسندگان

  • Mi-Ryoung Song
  • Samuel L. Pfaff
چکیده

Motor neurons are assigned unique subidentities preceding their axon navigation. This ensures proper innervation of muscle targets and is accompanied by a stereotypical clustering of motor neuron cell bodies into "motor pools" within the spinal cord. However, the mechanisms that drive motor neuron diversification have been poorly understood. A new study by Dasen et al. (2005) in this issue of Cell shows that a network of Hox genes is responsible for instructing motor pool development.

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عنوان ژورنال:
  • Cell

دوره 123  شماره 

صفحات  -

تاریخ انتشار 2005